This category is an easy one. The best Sandwich/Burger I had in 2008 was called a Honey Wasabi Turkey Burger from the Ingredient restaurant in downtown Lawrence. This burger was explosive and quite a pleasant surprise the first time I ate at Ingredient. The sandwich is described as "fresh seasoned ground turkey, provolone cheese, crisp lettuce, roma tomato with spicy sriracha aioli."
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Holy Crap, Rachael Ray ate at that joint!
http://www.foodnetwork.com/recipes/rachael-rays-tasty-travels/the-vortex-blue-shroom-burger-recipe/index.html
In L.A., and most of southern California for that matter, little hamburger stands are plentiful -- and since most of all of them purchase from the same foodservice distributor, there's an oddly constant taste to most of these non-related stands. And that taste is darn good. Too bad I don't get anything like that all where I live now.
But the best? Hard to narrow it down to just one. Haven't had one THAT good that it rises above the rest.
It's so good.